Differential associations of emotional and physical domains of the MacNew Heart with changes in 6-minute walking test

Abstract Aims Cardiac rehabilitation (CR), a key component of secondary prevention in cardiac patients, contributes fundamentally to improved cardiovascular health outcomes. Health-related quality life (HRQOL) represents widely employed outcome measure CR, yet, its predictive properties on exercise capacity change during CR are poorly understood. Aim this study was examine the association between baseline HRQOL and subdomains improvement CR. Methods Study participants were 13,717 inpatients six Swiss clinics from 2012 2018. We measured at admission with MacNew Heart (MNH) questionnaire discharge using six-minutes walking test (6MWT). Following factorial analyses, we performed univariate multivariate analyses global domains for capacity, adjusting demographic clinical characteristics. Results Mean 6MWT 114 meters (SD=90), achieved after 17.4 days (SD=5.5). Lower emotional (b=7.85, p≤0.001, 95% CI [−5.67, 10.03]) higher physical (b=−5.23, p<0.001, [−6.56, −3.90]) associated less 6MWT. Global MNH social showed no improvement. Conclusion Patients entering low high risk lower gain alone does not provide reliable assessment HRQOL; thus focus specific is needed. Funding Acknowledgement Type funding sources: None.